Description:  Pinky, Elmyra & the Brain is an animated sitcom that follows the mice Pinky and the Brain as they try to take over the world from the home of an overly affectionate girl named Elmyra Duff. The series began after the destruction of Acme Labs, leaving Pinky and Brain homeless and hiding inside a turtle, which Elmyra eventually buys. The main conflict stems from Brain's elaborate world domination plans being constantly thwarted by Elmyra's affection for them and Pinky's idiocy.

Premise: After their lab is destroyed, Pinky and the Brain end up in a pet store. Elmyra Duff purchases a turtle they are hiding inside, and the mice are forced to live in her house, which becomes their new base for world domination attempts.

Characters: The show features the main characters from Pinky and the Brain—the genius but easily frustrated Brain and the dim-witted Pinky—and Elmyra Duff, a character from Tiny Toon Adventures.

Conflict: Brain's plans are frequently interrupted not only by Pinky but also by Elmyra, who loves the animals to an extreme degree. She often hinders their schemes by treating them like pets.